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Article

Unraveling the genetic causes in large pedigrees with gout by whole‑exome sequencing.

International journal of molecular medicine - 1 Apr 2020

Xia Xiaoru, Jin Jing, Chen Zhen-Ji, Zhou Zhenni, Chen Hui, Zhang Chunwu, Zhang Linhua, Sun Li

Abstract excerpt

Gout is a common type of inflammatory arthritis that is clinically and genetically heterogeneous. The genetic aetiology remains unclear, and mainly relies on previous genome‑wide association studies focused on sporadic cases. The present study aimed to identify the genetic basis of gout in three families using whole‑exome sequencing (WES). WES was performed in the probands, and family members were involved in the...

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Identifiers

PMID: 32124961
DOI: 10.3892/ijmm.2020.4501
PMCID: PMC7053847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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