Article
SNPs in folate pathway are associated with the risk of nonsyndromic cleft lip with or without cleft palate, a meta-analysis.
Bioscience reports - 27 Mar 2020
Li Qiuyan, Xu Lidan, Jia Xueyuan, Saleem Komal, Zaib Tahir, Sun Wenjing, Fu Songbin
Abstract excerpt
BACKGROUND: Prenatal intake of folic acid is important for prevention of NSCL/P (nonsyndromic cleft lip with or without cleft palate). Associated genes in folate pathway are major enzymes of folic acid metabolism that is crucial for preventing birth defects. The present meta-analysis aims to investigate the association between four SNPs in folate pathway genes and the risk of NSCL/P. METHODS: Comprehensive...
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