Article
[Association study for gene polymorphism of folic acid/homocysteine metabolic pathway and nonsyndromic cleft lip with or without cleft palate in Chinese populations].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Jun 2013
Wang Ping, Wang Hong, Wu-chou Yah-huei, Ye Xiao-qian, Huang Shang-zhi, Shi Bing, Liang Kung-yee, Cao Wei-hua, Wu Tao, Beaty Terei H
Abstract excerpt
OBJECTIVE: To explore the association between 18 candidate genes encoding enzymes on the folate/homocysteine metabolism pathway and non-syndromic cleft lip with or without cleft palate (NSCL/P) in Chinese populations. METHODS: A total of 806 NSCL/P trios were drawn by an international consortium, which conducted a genome-wide association study using a case-parent trio design to investigate genes affecting risks...
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