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Article

Maternal polymorphisms in folic acid metabolic genes are associated with nonsyndromic cleft lip and/or palate in the Brazilian population.

Birth defects research. Part A, Clinical and molecular teratology - 1 Nov 2010

Bufalino Andreia, Ribeiro Paranaíba Lívia Máris, Nascimento de Aquino Sibele, Martelli-Júnior Hercílio, Oliveira Swerts Mario Sergio, Coletta Ricardo D

Abstract excerpt

BACKGROUND: Polymorphisms in genes that are involved in folic acid metabolism may be important maternal risk factors for the birth of a child with nonsyndromic cleft lip and/or palate (NSCL/P). The aim of this study was to determine the involvement of polymorphic variants in four genes (MTHFR, MT...

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Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

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Source

Identifiers

PMID: 20890936
DOI: 10.1002/bdra.20732

Genes

MTHFR
MTHFD1
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20890936-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Maternal polymorphisms in folic acid metabolic genes are associated with nonsyndromic cleft lip and/or palate in the Brazilian population.PMID 20890936Read ↗

Two SNPs rs1801133 and rs1801394 in folate pathway are associated with the risk of nonsyndromic cleft lip with or without cleft palateSemantic proximity Read ↗

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