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Article

Non-syndromic cleft lip with or without cleft palate in Asian populations: Association analysis on three gene polymorphisms of the folate pathway.

Archives of oral biology - 1 Jan 2016

Martinelli Marcella, Girardi Ambra, Cura Francesca, Nouri Nayereh, Pinto Valentina, Carinci Francesco, Morselli Paolo Giovanni, Salehi Mansoor, Scapoli Luca

Abstract excerpt

OBJECTIVE: Orofacial clefts (OFCs) are one of the most common birth defects in humans. They are the subject of a number of investigations aimed at elucidating the bases of their complex mode of inheritance involving both genetic and environmental factors. Genes belonging to the folate pathway have been among the most studied. The aim of the investigation was to replicate previous studies reporting evidence of...

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Source

Identifiers

PMID: 26540672
DOI: 10.1016/j.archoralbio.2015.10.019

Genes

CBS
MTHFR
TCN2

Variants

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