Article
Multi-omic features and clustering phenotypes of circulating tumor cells associated with metastasis and clinical outcomes.
International review of cell and molecular biology - 1 Jan 2025
Singh Anmol, Liu Huiping, El-Shennawy Lamiaa
Abstract excerpt
Metastasis is a lethal disease of cancer, spreading from primary tumors to the bloodstream as circulating tumor cells (CTCs), which disseminate to distant organs at low efficiency for secondary tumor regeneration, thereby contributing to unfavorable patient outcomes. The detection of dynamic CTC alterations can be indicative of cancer progression (residual cancer, aggressiveness, therapy resistance) or regression...
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