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The Detection and Morphological Analysis of Circulating Tumor and Host Cells in Breast Cancer Xenograft Models

5 Jul 2019

Abstract excerpt

Hematogenous dissemination may occur early in breast cancer (BC). Experimental models could clarify mechanisms, but in their development, the heterogeneity of this neoplasia must be considered. Here, we describe circulating tumor cells (CTCs) and the metastatic behavior of several BC cell lines in xenografts. MDA-MB-231, BT-474, MDA-MB-453 and MDA-MB-468 cells were injected at the orthotopic level in...

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PMID: 31284534
DOI: 10.3390/cells8070683

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