Article
A conduit to metastasis: circulating tumor cell biology.
Genes & development - 15 Sept 2017
Micalizzi Douglas S, Maheswaran Shyamala, Haber Daniel A
Abstract excerpt
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for detection and characterization of circulating tumor cells (CTCs) from patients with cancer. The analysis of CTCs has provided significant insight into the metastatic process. Studies on the biology of CTCs have begun to elucidate the molecular mechanisms of CTC generation, intravasation, survival, interactions with...
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