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Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs.

Advances in experimental medicine and biology - 1 Jan 2020

Vismara Marta, Reduzzi Carolina, Daidone Maria Grazia, Cappelletti Vera

Abstract excerpt

In metastatic breast cancer the role of circulating tumor cells (CTCs) enumeration for predicting clinical outcome is supported by many studies, most of them dealing with strictly epithelial cells. However, it is becoming clear that CTCs are a heterogeneous cell population characterized by plasticity and including also cells which have lost the epithelial phenotype. Here we review literature data on CTC...

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Breast Neoplasms
Neoplasm Metastasis
Neoplastic Cells, Circulating
Phenotype
Precision Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Single-Cell Analysis

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PMID: 32304081
DOI: 10.1007/978-3-030-35805-1_6

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