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Article

Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro.

Integrative biology : quantitative biosciences from nano to macro - 6 Mar 2020

Morgan Molly M, Schuler Linda A, Ciciliano Jordan C, Johnson Brian P, Alarid Elaine T, Beebe David J

Abstract excerpt

Accumulating evidence suggests that our ability to predict chemical effects on breast cancer is limited by a lack of physiologically relevant in vitro models; the typical in vitro breast cancer model consists of the cancer cell and excludes the mammary microenvironment. As the effects of the microenvironment on cancer cell behavior becomes more understood, researchers have called for the integration of the...

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Identifiers

PMID: 32118264
DOI: 10.1093/intbio/zyaa002
PMCID: PMC7060306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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