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Article

Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform.

BMC cancer - 2 Nov 2017

Lanz Henriette L, Saleh Anthony, Kramer Bart, Cairns Junmei, Ng Chee Ping, Yu Jia, Trietsch Sebastiaan J, Hankemeier Thomas, Joore Jos, Vulto Paul, Weinshilboum Richard, Wang Liewei

Abstract excerpt

BACKGROUND: Breast cancer is the most common invasive cancer among women. Currently, there are only a few models used for therapy selection, and they are often poor predictors of therapeutic response or take months to set up and assay. In this report, we introduce a microfluidic OrganoPlate® platform for extracellular matrix (ECM) embedded tumor culture under perfusion as an initial study designed to investigate...

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Identifiers

PMID: 29096610
DOI: 10.1186/s12885-017-3709-3
PMCID: PMC5668957

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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