Article

Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

2017-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Developmental cadmium exposure in vivo disrupts mammary gland differentiation, while exposure of breast cell lines to cadmium causes invasion consistent with the epithelial-mesenchymal transition (EMT). The effects of cadmium on normal human breast stem cell development have not been measured. <h4>Objective</h4> The objective of this study was to quantify the effects of c...

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Literature Corpus work: 767b4b05-f83b-5332-8f22-405c3f9421d9
DOI: 10.1101/208157

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