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Article

Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.

Addiction biology - 1 Mar 2021

Luo Xingguang, Guo Xiaoyun, Luo Xingqun, Tan Yunlong, Zhang Ping, Yang Kebing, Xie Ting, Shi Jing, Zhang Yong, Xu Jianying, Zuo Lingjun, Li Chiang-Shan R

Abstract excerpt

The gray matter volume (GMV) of the putamen has been reported to be regulated by kinectin 1 gene (KTN1). As a hub of the dopaminergic circuit, the putamen is widely implicated in the etiological processes of substance use disorders (SUD). Here, we aimed to identify robust and reliable associations between KTN1 SNPs and SUD across multiple samples. We examined the associations between SUD and KTN1 SNPs in four...

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Identifiers

PMID: 32115811
DOI: 10.1111/adb.12888
PMCID: PMC7641293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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