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Article

3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways.

Journal of molecular endocrinology - 1 May 2020

Jain Lekha, Fadason Tayaza, Schierding William, Vickers Mark H, O'Sullivan Justin M, Perry Jo K

Abstract excerpt

Growth hormone (GH) is a peptide hormone predominantly produced by the anterior pituitary and is essential for normal growth and metabolism. The GH locus contains five evolutionarily related genes under the control of an upstream locus control region that coordinates tissue-specific expression of these genes. Compromised GH signalling and genetic variation in these genes has been implicated in various disorders...

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PMID: 32106092
DOI: 10.1530/JME-20-0010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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