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The New Genomics: What Molecular Databases Can Tell Us About Human Population Variation and Endocrine Disease.

Endocrinology - 1 Jul 2017

Rotwein Peter

Abstract excerpt

Major recent advances in genetics and genomics present unique opportunities for enhancing our understanding of human physiology and disease predisposition. Here I demonstrate how analysis of genomic information can provide new insights into endocrine systems, using the human growth hormone (GH) signaling pathway as an illustrative example. GH is essential for normal postnatal growth in children, and plays...

Topics

Databases, Chemical
Endocrine System Diseases
Genetic Variation
Genomics
Human Growth Hormone
Humans
Polymorphism, Genetic
Receptors, Somatotropin
Signal Transduction

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 28498917
DOI: 10.1210/en.2017-00338
PMCID: PMC7282473

Genes

JAK2
GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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