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Article

Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease.

Human genetics - 1 Aug 2007

Rodriguez Santiago, Gaunt Tom R, Day Ian N M

Abstract excerpt

The human growth hormone gene (GH1) and the insulin-like growth factor 1 and 2 genes (IGF1 and IGF2) encode the central elements of a key pathway influencing growth in humans. This "growth pathway" also includes transcription factors, agonists, antagonists, receptors, binding proteins, and endocrine factors that constitute an intrincate network of feedback loops. GH1 is evolutionarily coupled with other genes in...

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Source

Identifiers

PMID: 17534663
DOI: 10.1007/s00439-007-0378-3

Genes

IGF1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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