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Article

Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling.

Nature communications - 25 Feb 2020

Ma Guolin, He Lian, Liu Shuzhong, Xie Jiansheng, Huang Zixian, Jing Ji, Lee Yi-Tsang, Wang Rui, Luo Hesheng, Han Weidong, Huang Yun, Zhou Yubin

Abstract excerpt

Genetically encoded photoswitches have enabled spatial and temporal control of cellular events to achieve tailored functions in living cells, but their applications to probe the structure-function relations of signaling proteins are still underexplored. We illustrate herein the incorporation of various blue light-responsive photoreceptors into modular domains of the stromal interaction molecule 1 (STIM1) to...

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Identifiers

PMID: 32098964
DOI: 10.1038/s41467-020-14841-9
PMCID: PMC7042325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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