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Article

Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies

21 Feb 2020

Abstract excerpt

All B cell leukaemias and a substantial fraction of lymphomas display a natural niche residency in the bone marrow. While the bone marrow compartment may only be one of several sites of disease manifestations, the strong clinical significance of minimal residual disease (MRD) in the bone marrow strongly suggests that privileged niches exist in this anatomical site favouring central elements of malignant...

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PMID: 32098106
DOI: 10.3390/ijms21041466

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