Article

Lymphoma B cells remodel bone marrow stromal cell organization and function to induce a supportive cancer-associated fibroblast network

2023-09-28

Abstract excerpt

<h4>ABSTRACT</h4> Bone marrow (BM) involvement is a common feature of lymphomas deriving from germinal-center B cells and is associated with a bad prognosis. In particular, follicular lymphoma (FL) infiltrates the BM in 70% of cases, in association with a remodeling of surrounding tumor microenvironment. Analysis of in vitro -expanded FL mesenchymal stromal cells (MSCs) revealed an extensive alteration of BM str...

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Literature Corpus work: ec97c752-4a19-5661-be39-d13c9cb99d37
DOI: 10.1101/2023.09.26.559605

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