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Article

Polymorphisms of SOCS-1 Are Associated With a Rapid HIV Progression Rate.

Journal of acquired immune deficiency syndromes (1999) - 1 Jun 2020

Hersberger Martin, Schlaepfer Erika, Buehler Marco, Bochud Pierre-Yves, Vernazza Pietro, Marti-Jaun Jacqueline, Nemeth Johannes, Zwahlen Marcel, Schmidlin Kurt, Speck Roberto F

Abstract excerpt

OBJECTIVES: Immune activation, among others driven by interferon (IFN)-α and IFN-γ activation, is a main feature of progressive HIV infection. Suppressor of cytokine signaling (SOCS) 1 and 3 are negative feedback regulators of the IFN-α and IFN-γ axis. Here, we analyzed the role of 9 single-nucleotide polymorphisms (SNPs) within SOCS-1 and SOCS-3 genes for their association with an HIV progression rate in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32097250
DOI: 10.1097/QAI.0000000000002319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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