Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort.

doi:10.1097/QAD.0000000000000632

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Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort.

AIDS (London, England) - 15 May 2015

Zhang Yonghong, Makvandi-Nejad Shokouh, Qin Ling, Zhao Yan, Zhang Tong, Wang Lili, Repapi Emmanouela, Taylor Stephen, McMichael Andrew, Li Ning, Dong Tao, Wu Hao

Abstract excerpt

BACKGROUND: The interferon-inducible transmembrane protein-3 (IFITM3) is a protein that restricts multiple pathogenic viruses such as influenza virus. The single-nucleotide polymorphism rs12252-C, which is rare in Caucasian populations, but much more common in the Han Chinese population, has been found in much higher homozygous frequency in patients with severe acute influenza. Until now, there has been no study...

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PMID: 25784441
DOI: 10.1097/QAD.0000000000000632
PMCID: PMC4442129

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IFITM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort.PMID 25784441Read ↗

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High Level Antibody Response to Pandemic Influenza H1N1/09 Virus Is Associated With Interferon-Induced Transmembrane Protein-3 rs12252-CC in Young Adults.Semantic proximity Read ↗

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