Article
A genome-wide multiphenotypic association analysis identified candidate genes and gene ontology shared by four common risky behaviors.
Aging - 22 Feb 2020
Ye Jing, Liu Li, Xu Xiaoqiao, Wen Yan, Li Ping, Cheng Bolun, Cheng Shiqiang, Zhang Lu, Ma Mei, Qi Xin, Liang Chujun, Kafle Om Prakash, Wu Cuiyan, Wang Sen, Wang Xi, Ning Yujie, Chu Xiaomeng, Niu Lin, Zhang Feng
Abstract excerpt
BACKGROUND: Risky behaviors can lead to huge economic and health losses. However, limited efforts are paid to explore the genetic mechanisms of risky behaviors. RESULT: MASH analysis identified a group of target genes for risky behaviors, such as APBB2, MAPT and DCC. For GO enrichment analysis, FUMA detected multiple risky behaviors related GO terms and brain related diseases, such as regulation of neuron...
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