Article

The pleiotropic architecture of human impulsivity across biological scales

2023-11-29

Abstract excerpt

Impulsivity is a complex psychological construct that represents a core feature of many psychiatric and neurological conditions. Here, we used multivariate methods to formally model the genetic architecture of impulsivity in humans, advancing genomic discovery and revealing pervasive pleiotropy that largely counters theories of impulsivity as a unitary construct. We identified 18 loci and 93 genes with diverse eff...

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Literature Corpus work: 7552754e-c6cf-5b60-8380-2a0d7c639930
DOI: 10.1101/2023.11.28.23299133

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