Article
A multi-dimensional characterization of anxiety in monozygotic twin pairs reveals susceptibility loci in humans.
Translational psychiatry - 11 Dec 2017
Alisch Reid S, Van Hulle Carol, Chopra Pankaj, Bhattacharyya Anita, Zhang Su-Chun, Davidson Richard J, Kalin Ned H, Goldsmith H Hill
Abstract excerpt
The etiology of individual differences in human anxiousness is complex and includes contributions from genetic, epigenetic (i.e., DNA methylation) and environmental factors. Past genomic approaches have been limited in their ability to detect human anxiety-related differences in these factors. To overcome these limitations, we employed both a multi-dimensional characterization method, to select monozygotic twin...
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