Article

Shared Genetic Architecture and Neurobiological Pathways of Problematic Alcohol Use and Anxiety Disorders

2025-11-27

Abstract excerpt

<h4>Background</h4> Problematic alcohol use (PAU) and anxiety disorders (ANX) frequently co-occur, implying shared genetic and neurobiological foundations. However, the directionality of potential causal relationships and the specific mechanisms underlying the overlap remain unclear. Thus, we investigated the shared genetic architecture and neurobiological pathways between PAU and ANX using a multimethod genomic...

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Literature Corpus work: a553b2bf-6a6e-5e8f-9797-dc16774710c5
DOI: 10.1101/2025.11.24.25339061

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