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Article

Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking.

Translational psychiatry - 8 Sept 2021

Hindley Guy, Bahrami Shahram, Steen Nils Eiel, O'Connell Kevin S, Frei Oleksandr, Shadrin Alexey, Bettella Francesco, Rødevand Linn, Fan Chun C, Dale Anders M, Djurovic Srdjan, Smeland Olav B, Andreassen Ole A

Abstract excerpt

Increased risk-taking is a central component of bipolar disorder (BIP) and is implicated in schizophrenia (SCZ). Risky behaviours, including smoking and alcohol use, are overrepresented in both disorders and associated with poor health outcomes. Positive genetic correlations are reported but an improved understanding of the shared genetic architecture between risk phenotypes and psychiatric disorders may provide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 34497263
DOI: 10.1038/s41398-021-01576-4
PMCID: PMC8426401

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