Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia.

Nucleic acids research - 17 Apr 2020

Moffitt Andrea B, Spector Mona S, Andrews Peter, Kendall Jude, Alexander Joan, Stepansky Asya, Ma BeiCong, Kolitz Jonathan, Chiorazzi Nicholas, Allen Steven L, Krasnitz Alex, Wigler Michael, Levy Dan, Wang Zihua

Abstract excerpt

Measuring minimal residual disease in cancer has applications for prognosis, monitoring treatment and detection of recurrence. Simple sequence-based methods to detect nucleotide substitution variants have error rates (about 10-3) that limit sensitive detection. We developed and characterized the performance of MASQ (multiplex accurate sensitive quantitation), a method with an error rate below 10-6. MASQ counts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Neoplasm, Residual

Share to Pilot Projects

Share to Recurrence

Share to Remission Induction

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 32083660
DOI: 10.1093/nar/gkaa090
PMCID: PMC7144909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia.PMID 32083660Read ↗

Ultrasensitive detection of acute myeloid leukemia minimal residual disease using single molecule molecular inversion probesSemantic proximity Read ↗

Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring.Semantic proximity Read ↗

Ultrasensitive mutation detection identifies rare residual cells causing acute myelogenous leukemia relapse.Semantic proximity Read ↗

Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemiaSemantic proximity Read ↗

Accurate and Sensitive Analysis of Minimal Residual Disease in Acute Myeloid Leukemia Using Deep Sequencing of Single Nucleotide VariationsSemantic proximity Read ↗

Accurate detection of subclonal variants in paired diagnosis-relapse acute myeloid leukemia samples by next generation Duplex Sequencing.Semantic proximity Read ↗

Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemiaSemantic proximity Read ↗

Single-cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia.Semantic proximity Read ↗

Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemiaSemantic proximity Read ↗

Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing.Semantic proximity Read ↗

Calibration-free NGS quantitation of mutations below 0.01% VAF.Semantic proximity Read ↗

Patient-tailored analysis of minimal residual disease in acute myeloid leukemia using next-generation sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.