Ultrasensitive detection of acute myeloid leukemia minimal residual disease using single molecule molecular inversion probes

Abstract excerpt

The identification of minimal residual disease is the primary diagnostic finding which predicts relapse in patients treated for acute myeloid leukemia. Ultrasensitive detection of minimal residual disease would enable better patient risk stratification and could open opportunities for early therapeutic intervention. Herein we apply single molecule molecular inversion probe capture, a technology combining...

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