Article
The HLA A03 Supertype and Several Pan Species Major Histocompatibility Complex Class I A Allotypes Share a Preference for Binding Positively Charged Residues in the F Pocket: Implications for Controlling Retroviral Infections.
Journal of virology - 16 Apr 2020
de Groot Natasja G, Heijmans Corrine M C, de Ru Arnoud H, Otting Nel, Koning Frits, van Veelen Peter A, Bontrop Ronald E
Abstract excerpt
The major histocompatibility complex (MHC) class I region of humans, chimpanzees (Pan troglodytes), and bonobos (Pan paniscus) is highly similar, and orthologues of HLA-A, -B, and -C are present in both Pan species. Based on functional characteristics, the different HLA-A allotypes are classified into different supertypes. One of them, the HLA A03 supertype, is widely distributed among different human...
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