Article
Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2000
McKinney D M, Erickson A L, Walker C M, Thimme R, Chisari F V, Sidney J, Sette A
Abstract excerpt
We have sequenced the Pan troglodytes class I (Patr) molecules from three common chimpanzees and expressed them as single molecules in a class I-deficient cell line. These lines were utilized to obtain purified class I molecules to define the peptide binding motifs associated with five different Patr molecules. Based on these experiments, as well as analysis of the predicted structure of the B and F polymorphic...
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