Article
Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Inflammatory bowel diseases - 1 Mar 2013
Hirano Atsushi, Yamazaki Keiko, Umeno Junji, Ashikawa Kyota, Aoki Masayuki, Matsumoto Takayuki, Nakamura Shotaro, Ninomiya Toshiharu, Matsui Toshiyuki, Hirai Fumihito, Kawaguchi Takaaki, Takazoe Masakazu, Tanaka Hiroki, Motoya Satoshi, Kiyohara Yutaka, Kitazono Takanari, Nakamura Yusuke, Kamatani Naoyuki, Kubo Michiaki
Abstract excerpt
BACKGROUND: A large-scale meta-analysis of a series of European genome-wide association studies revealed 71 susceptibility loci for Crohn's disease (CD). However, it is not clear whether these susceptibility loci are also shared with Japanese populations. METHODS: We genotyped 71 single-nucleotide polymorphisms (SNPs) comprising 1311 CD cases and 6585 controls of Japanese descent, and their associations with CD...
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