Article
Genetic characteristics of inflammatory bowel disease in a Japanese population.
Journal of gastroenterology - 1 Jul 2016
Fuyuno Yuta, Yamazaki Keiko, Takahashi Atsushi, Esaki Motohiro, Kawaguchi Takaaki, Takazoe Masakazu, Matsumoto Takayuki, Matsui Toshiyuki, Tanaka Hiroki, Motoya Satoshi, Suzuki Yasuo, Kiyohara Yutaka, Kitazono Takanari, Kubo Michiaki
Abstract excerpt
BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC) are two major forms of inflammatory bowel disease (IBD). Meta-analyses of genome-wide association studies (GWAS) have identified 163 susceptibility loci for IBD among European populations; however, there is limited information for IBD susceptibility in a Japanese population. METHODS: We performed a GWAS using imputed genotypes of 743 IBD patients (372...
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