Article
Case-control study of IL23R rs76418789 polymorphism, smoking, and ulcerative colitis in Japan.
Cytokine - 1 Nov 2024
Miyake Yoshihiro, Tanaka Keiko, Nagata Chisato, Furukawa Shinya, Andoh Akira, Yokoyama Tetsuji, Yoshimura Naoki, Mori Kenichiro, Ninomiya Tomoyuki, Yamamoto Yasunori, Takeshita Eiji, Ikeda Yoshio, Saito Mitsuru, Ohashi Katsuhisa, Imaeda Hirotsugu, Kakimoto Kazuki, Higuchi Kazuhide, Nunoi Hiroaki, Mizukami Yuji, Suzuki Seiyuu, Hiraoka Sakiko, Okada Hiroyuki, Kawasaki Keitarou, Higashiyama Masaaki, Hokari Ryota, Miura Hiromasa, Miyake Teruki, Kumagi Teru, Kato Hiromasa, Hato Naohito, Sayama Koji, Hiasa Yoichi
Abstract excerpt
BACKGROUND: Interleukin (IL)-23 is involved in the pathogenesis of ulcerative colitis (UC). A genome-wide significant association between IL23R p.G149R (rs76418789) and UC was previously identified in Japan and Korea. This case-control study aims to examine this association within the Japanese population. METHODS: The study included 384 cases diagnosed with UC within the past 4 years and 661 control subjects....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.