Article
JMJD1B, a novel player in histone H3 and H4 processing to ensure genome stability.
Epigenetics & chromatin - 18 Feb 2020
Saavedra Francisco, Gurard-Levin Zachary A, Rojas-Villalobos Camila, Vassias Isabelle, Quatrini Raquel, Almouzni Geneviève, Loyola Alejandra
Abstract excerpt
BACKGROUND: Maintaining a proper supply of soluble histones throughout the cell cycle is important to ensure chromatin and genome stability. Following their synthesis, histones undergo a series of maturation steps to prepare them for deposition onto chromatin. RESULTS: Here, we identify the lysine demethylase JMJD1B as a novel player in the maturation cascade that contributes to regulate histone provision. We...
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