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Article

Effects of COMT rs4680 and BDNF rs6265 polymorphisms on brain degree centrality in Han Chinese adults who lost their only child.

Translational psychiatry - 30 Jan 2020

Qi Rongfeng, Luo Yifeng, Zhang Li, Weng Yifei, Surento Wesley, Li Lingjiang, Cao Zhihong, Lu Guang Ming

Abstract excerpt

Losing one's only child is a major traumatic life event that may lead to posttraumatic stress disorder (PTSD); however, not all parents who experience this trauma develop PTSD. Genetic variants are associated with the risk of developing PTSD. Catechol-O-methyltransferase (COMT) rs4680 and brain-derived neurotrophic factor (BDNF) rs6265 are two most well-described single-nucleotide polymorphisms that relate to...

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Identifiers

PMID: 32066722
DOI: 10.1038/s41398-020-0728-7
PMCID: PMC7026113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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