Article
The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development.
Development (Cambridge, England) - 1 Feb 2012
Bedell Victoria M, Person Anthony D, Larson Jon D, McLoon Anna, Balciunas Darius, Clark Karl J, Neff Kevin I, Nelson Katie E, Bill Brent R, Schimmenti Lisa A, Beiraghi Soraya, Ekker Stephen C
Abstract excerpt
The Homeobox (Hox) and Paired box (Pax) gene families are key determinants of animal body plans and organ structure. In particular, they function within regulatory networks that control organogenesis. How these conserved genes elicit differences in organ form and function in response to evolutionary pressures is incompletely understood. We molecularly and functionally characterized one member of an evolutionarily...
Topics
- Animals
- Animals, Genetically Modified
- Biological Evolution
- Biomarkers
- Branchial Region
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Gene Knockdown Techniques
- Kidney