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Article

miRNA-mRNA Profiling Reveals Prognostic Impact of SMC1A Expression in Acute Myeloid Leukemia.

Oncology research - 29 May 2020

Gadewal Nikhil, Kumar Rohit, Aher Swapnil, Gardane Anagha, Gaur Tarang, Varma Ashok K, Khattry Navin, Hasan Syed K

Abstract excerpt

Acute myeloid leukemia (AML) with NPM1 mutation is a disease driving genetic alteration with good prognosis. Although it has been suggested that NPM1 mutation induces chemosensitivity in leukemic cells, the underlying cause for the better survival of NPM1 mutated patients is still not clear. Mutant NPM1 AML has a unique microRNA and their target gene (mRNA) signature compared to wild-type NPM1. Dynamic regulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

Share to MicroRNAs

Share to Nucleophosmin

Share to RNA Interference

Share to Structural Maintenance of Chromosome Protein 1

Source

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Identifiers

PMID: 32059753
DOI: 10.3727/096504020X15816752427321
PMCID: PMC7851519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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