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[Clinical Significance of Low Expression of LncRNA CASC15 in Acute Myeloid Leukemia with NPM1 Mutations].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2022

Xia Pei-Hui, Xu Zi-Jun, Jin Ye, Ma Ji-Chun, Wen Xiang-Mei, Yuan Qian, Leng Jia-Yan, Qian Jun, Lin Jiang

Abstract excerpt

AbstractObjective: To identify the expression and methylation patterns of lncRNA CASC15 in bone marrow (BM) samples of acute myeloid leukemia (AML) patients, and further explore its clinical significance. METHODS: Eighty-two de novo AML patients and 18 healthy donors were included in the study. Meanwhile, seven public datasets from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) were included to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35680788
DOI: 10.19746/j.cnki.issn.1009-2137.2022.03.002

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