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MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

13 Mar 2008

Abstract excerpt

Acute myeloid leukemia (AML) is a highly diverse disease characterized by various cytogenetic and molecular abnormalities. MicroRNAs are small noncoding RNAs that show variable expression during myeloid differentiation. MicroRNA expression in marrow blasts in 215 cases of newly diagnosed and (cyto)genetically defined AML was assessed using quantitative reverse-transcription-polymerase chain reaction (RT-PCR) for...

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PMID: 18337557
DOI: 10.1182/blood-2008-01-133355

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