Article

MiR-10a-5p regulates proliferation, apoptosis and cell cycle of NPM1-mutated acute myeloid leukemia cells by targeting SHANK3

2020-11-10

Abstract excerpt

<h4>Objective: </h4> Although NMP1 mutation plays a crucial role in regulating the occurrence and development of acute myeloid leukemia (AML), there is still a lack of effective means to improve the prognosis of AML. Studies showed that miR-10a-5p is significantly highly expressed in leukemia and other cancers. However, the function and mechanism of miR-10a-5p in NPM1-mutated AML remain unclear. <h4>Methods: </h4>...

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Literature Corpus work: bfcb4d12-9476-5ba6-8e8f-455d62f79394
DOI: 10.21203/rs.3.rs-103100/v1

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