Article
A case report of multiple primary prostate tumors with differential drug sensitivity.
Nature communications - 13 Feb 2020
Wilkinson Scott, Harmon Stephanie A, Terrigino Nicholas T, Karzai Fatima, Pinto Peter A, Madan Ravi A, VanderWeele David J, Lake Ross, Atway Rayann, Bright John R, Carrabba Nicole V, Trostel Shana Y, Lis Rosina T, Chun Guinevere, Gulley James L, Merino Maria J, Choyke Peter L, Ye Huihui, Dahut William L, Turkbey Baris, Sowalsky Adam G
Abstract excerpt
Localized prostate cancers are genetically variable and frequently multifocal, comprising spatially distinct regions with multiple independently-evolving clones. To date there is no understanding of whether this variability can influence management decisions for patients with prostate tumors. Here, we present a single case from a clinical trial of neoadjuvant intense androgen deprivation therapy. A patient was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.