Article
MICA-129 Met/Val polymorphism could be a genetic biomarker for Familial Breast Cancer in the Tunisian population.
International journal of immunogenetics - 1 Oct 2020
Ouni Nesrine, Ben Chaaben Arij, Ayari Fayza, Douik Hayet, Guizani Imen, Benammar-Elgaaied Amel, Guemira Fethi, Tamouza Ryad
Abstract excerpt
Identification of candidate genes associated with susceptibility of breast cancer can have a significant impact at a cancer management national healthcare systems level, making genetic testing more affordable and cost-effective. We have previously shown that the major histocompatibility complex class I-related chain A (MICA) was related to breast cancer and plays an important role in modulating immune response...
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