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HLA class II polymorphism: protective or risk factors to breast cancer in Tunisia?

Pathology oncology research : POR - 1 Jan 2006

Baccar Harrath Amal, Yacoubi Loueslati Besma, Troudi Wafa, Hmida Slama, Sedkaoui Syrine, Dridi Amel, Jridi Afef, Ben Ayed Farhat, Ben Rhomdhane Khaled, Ben Ammar Elgaaied Amel

Abstract excerpt

HLA system plays a key role in the tumor cells' escape from immune surveillance. Herein is the first report on the correlation of the susceptibility to breast cancer with HLA class II markers in Tunisia. Molecular typing of HLA-DRB1 and -DQB1 loci was undertaken for 70 Tunisian female patients. Comparison of allele and haplotype distribution between patients and 70 female control subjects reveals a negative...

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PMID: 16799707
DOI: 10.1007/BF02893448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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