HER2 polymorphisms and breast cancer in Tunisian women.

doi:10.1089/gtmb.2009.0069

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HER2 polymorphisms and breast cancer in Tunisian women.

Genetic testing and molecular biomarkers - 1 Feb 2010

Kallel Imen, Kharrat Najla, Al-fadhly Suad, Rebai Maha, Khabir Abdelmajid, Boudawara Tahia Sallemi, Rebaï Ahmed

Abstract excerpt

HER2 has been thought to play a critical role in both breast cancer development and progression. Any functional polymorphisms can potentially affect breast cancer risk as well as cancer phenotype and outcome. In our study, we analyzed three polymorphisms in the HER2 gene: the single-nucleotide polymorphism (SNP) HER2 Ile(655)Val as well as another SNP (rs903506) close to it and a new screened dinucleotide repeat...

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PMID: 19929405
DOI: 10.1089/gtmb.2009.0069

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