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MICA-129Met/Val Polymorphism Is Associated with Early-Onset Breast Cancer Risk.

Immunological investigations - 1 Aug 2017

Ouni Nesrine, Ben Chaaben Arij, Kablouti Ghalia, Lajnef Mohamed, Ayari Fayza, Abaza Hajer, Damak Tarek, Harzallah Latifa, Benammar-Elgaaeid Amel, Guemira Fethi, Tamouza Ryad

Abstract excerpt

The major histocompatibility complex class I-related chain A (MICA), expressed on cell surface, plays an important role in the elimination of both virus-infected cells and tumor through the activation of the natural killer (NK) receptor NKG2D. A polymorphic change from methionine (Met) to valine (Val) at amino acid position 129 categorizes MICA alleles into strong and weak binders for the NKG2D receptor and has...

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Identifiers

PMID: 28742417
DOI: 10.1080/08820139.2017.1336175

Genes

MICA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MICA-129Met/Val Polymorphism Is Associated with Early-Onset Breast Cancer Risk.PMID 28742417Read ↗

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