Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians.

doi:10.1007/s10549-012-2202-6

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Article

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians.

Breast cancer research and treatment - 1 Oct 2012

Shan Jingxuan, Mahfoudh Wijden, Dsouza Shoba P, Hassen Elham, Bouaouina Noureddine, Abdelhak Sonia, Benhadjayed Ahlem, Memmi Hager, Mathew Rebecca Ann, Aigha Idil I, Gabbouj Sallouha, Remadi Yassmine, Chouchane Lotfi

Abstract excerpt

Genome-wide Association Studies (GWAS) revealed novel genetic markers for breast cancer susceptibility. But little is known about the risk factors and molecular events associated with breast cancer in Arab Population. Therefore, we designed a broad study to investigate the susceptibility and prognostic implications of the GWAS breast cancer loci in the Tunisian population. In a cohort of 640 unrelated patients...

Topics

Adult
Aged
Aged, 80 and over
Apoptosis Regulatory Proteins
Arabs
Breast Neoplasms
Case-Control Studies
Chromosomes, Human, Pair 2
Chromosomes, Human, Pair 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genetic Predisposition to Disease

Genome-Wide Association Study

Heterozygote

High Mobility Group Proteins

Humans

MAP Kinase Kinase Kinase 1

Middle Aged

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 22910930
DOI: 10.1007/s10549-012-2202-6
PMCID: PMC3439608

Genes

FGFR2

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