Article
Association of HLA-G +3142 C>G polymorphism and breast cancer in Tunisian population.
Immunologic research - 1 Aug 2016
Zidi Inès, Dziri Olfa, Zidi Nour, Sebai Refaat, Boujelebene Nadia, Ben Hassine Amna, Ben Yahia Hamza, Laaribi Ahmed Baligh, Babay Wafa, Rifi Hela, Mezlini Amel, Chelbi Hanene
Abstract excerpt
HLA-G is highly expressed in cancer. Also, it is associated to its progression. Here, we explored the relationship between two HLA-G polymorphisms with breast cancer (BC) and tried to make a correlation with sHLA-G levels. We genotyped 104 patients with BC and 83 controls (CTRL) for HLA-G 14-bp insertion/deletion (Ins/Del) and HLA-G +3142 C>G polymorphisms. The mutations were identified with PCR and PCR-RFLP. The...
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