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Article

Study of the association of LILRB2 gene polymorphisms with colorectal cancer susceptibility and prognosis in Tunisian population.

Human immunology - 1 Feb 2026

Ferjani Malek, Dhouioui Sabrine, Bourogâa Hager, Jalouli Maroua, Boujelbene Nadia, Zemni Inès, Harrath Abdel Halim, Ayadi Mohamed Ali, Zidi Inès

Abstract excerpt

BACKGROUND: leukocyte immunoglobulin-like receptors subfamily B member 2 (LILRB2), a receptor with immunosuppressive properties belonging to the Leucocytes Ig-Like receptors (LILR) family, is extensively detected in various tumor tissues. Its major ligand, human leukocyte antigen G (HLA-G), is pivotal in enabling tumor immune escape. This study sought to investigate the potential impact of LILRB2 gene...

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Identifiers

PMID: 41418557
DOI: 10.1016/j.humimm.2025.111635

Genes

LILRB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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