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Article

Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.

Biochemical pharmacology - 1 Jun 2020

Peleli Maria, Bibli Sofia-Iris, Li Zhen, Chatzianastasiou Athanasia, Varela Aimilia, Katsouda Antonia, Zukunft Sven, Bucci Mariarosaria, Vellecco Valentina, Davos Constantinos H, Nagahara Noriyuki, Cirino Giuseppe, Fleming Ingrid, Lefer David J, Papapetropoulos Andreas

Abstract excerpt

RATIONALE: Hydrogen sulfide (H2S) is a physiological mediator that regulates cardiovascular homeostasis. Three major enzymes contribute to the generation of endogenously produced H2S, namely cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST). Although the biological roles of CSE and CBS have been extensively investigated in the cardiovascular system, very...

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Identifiers

PMID: 32027885
DOI: 10.1016/j.bcp.2020.113833
PMCID: PMC7657663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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