Article
The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock.
Shock (Augusta, Ga.) - 1 Apr 2019
Gröger Michael, Wepler Martin, Wachter Ulrich, Merz Tamara, McCook Oscar, Kress Sandra, Lukaschewski Britta, Hafner Sebastian, Huber-Lang Markus, Calzia Enrico, Georgieff Michael, Nagahara Noriyuki, Szabó Csaba, Radermacher Peter, Hartmann Clair
Abstract excerpt
INTRODUCTION: Hemorrhagic shock is a major cause of death after trauma. An additional blunt chest trauma independently contributes to mortality upon the development of an acute lung injury (ALI) by aggravating pathophysiological consequences of hemorrhagic shock. The maintenance of hydrogen sulfide availability is known to play an important role during hemorrhage and ALI. We therefore tested the impact of a...
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